Intravenous Fluosol intheTreatment ofAcuteMyocardial Infarction Results oftheThrombolysis andAngioplasty inMyocardial Infarction 9Trial
1994
ofmyocardial salvage after reperfusion maybe limited byanatomicandmetabolicconsequencesofreperfusion.4,5Thisphenomenon,referredtoasreperfusioninjury,hasbeen limited in animal models byFluosol, a perfluoro-chemicalemulsion.Thesestudieshavereportedthattheintracoronary administration ofoxygenated Fluosol re-sulted in smaller infarct size and improved systolic LVfunction.6-8 Supportive evidence ofbeneficial effects, interms of both preservation of the microvasculatureandmoresubstantial salvageofmyocardium,hasbeendeveloped.
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