Distribution of CTLA-4 polymorphisms in allergic asthma.

Monika Jasek,Wioleta Łuszczek,Andrzej Obojski,Beata Winiarska,Katarzyna Hałubek,Izabela Nowak,Maria Mańczak,Andrzej Wiśniewski,Andrzej Pawlik,Anna Jonkisz,Arleta Lebioda,Edyta Majorczyk,Tadeusz Dobosz,Piotr Kuśnierczyk

Distribution of CTLA-4 polymorphisms in allergic asthma.

2006

Monika Jasek
Wioleta Łuszczek
Andrzej Obojski
Beata Winiarska
Katarzyna Hałubek
Izabela Nowak
Maria Mańczak
Andrzej Wiśniewski
Andrzej Pawlik
Anna Jonkisz
Arleta Lebioda
Edyta Majorczyk
Tadeusz Dobosz
Piotr Kuśnierczyk

Background: The CTLA-4 molecule is an important negative regulator of T cell activation. It is encoded on chromosome 2q33 and found to be associated with several allergic phenotypes

Keywords:

Immunology
Allergy
Gene polymorphism
Single-nucleotide polymorphism
Polymorphism (computer science)
Asthma
Regulator
T cell
Biology
CTLA-4
Genotype
Phenotype
Immunopathology

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