Abstract 19776: 3 to 5 Years Outcomes of TAVR vs SAVR for High Surgical Risk Patients, a Systematic Review and Metanalysis

Background: The comparative benefits and harms of transcatheter aortic valve intervention and surgical aortic valve replacement for high surgical risk patients with aortic stenosis haven’t shown any significant statistical and clinical difference up to 2 years. However, the comparison has not been well characterized beyond 3 years. This meta-analysis aims to assess the differential outcomes of TAVR and SAVR in high surgical risk patients enrolled in randomized controlled trials with at least 3 years of follow up.METHODS We performed a systematic literature review to identify randomized and nonrandomized clinical studies that reported at least 3 years outcomes of transcatheter aortic valve replacement vs surgical aortic valve replacement for high surgical risk patients with aortic stenosis. A total of 8 databases including Pubmed (Medline), Embase, Cochrane Library, ACP Journal Club, Scopus, DARE and Ovid containing articles from January 2000 to March 2017 were analyzed. Results: We were able to identify a...