The Great Escape: Mgr2 of the Mitochondrial TIM23 Translocon Is a Gatekeeper Tasked with Releasing Membrane Proteins

By using a combination of biochemistry and genetics, in this issue of Molecular Cell Ieva et al. (2014) uncover an unexpected role for Mgr2 of the mitochondrial TIM23 translocon as a gatekeeper in the release of membrane proteins from the translocon.