Study progress of the stereotyped B-cell receptor in chronic lymphocytic leukemia: reports in the 54 ASH annual meeting

B-cell receptors play an important role in the mechanism of chronic lymphocytic leukemia.Distinct CLL B-cell receptors exhibit particular biological features and behaviors to specific modes of microenvironmental interactions leading to clonal evolution and adverse outcome. Key words: B-cell receptor; Leukemia, lymphocytic, chronic; ASH onnual meeting