Curative effect survey of primary hypertension treated by amlodipine besylate tablets and extended release nifedipine tablets

Objective:To evaluate the and safety of amlodipine besylate tablets and extended release nifedipine tablets forpatient swith mild and moderate essential hypertension.Methods:Two hundred caseswith essential hypertensionwere divided randomly into 2 groups:amlodipine besylate tablets and extended release nifedipine.Treatment lasted for 8 weeks.Parameters of blood pressure was measured before and after treatmen.Results:Blood pressurewere significantly reduced in both groups after treatment(P0.01).There was no significant difference in responder rates between patients taking amlodipine besylate tablets(95%)and patients taking extended release nifedipine(86%).The untoward reaction in patients taking amlodipine besylate tablets(5%) is lower than that in patients taking extended release nifedipine(14%)(P0.05).Conclusion:amlodipine besylate tablets is new drug which has effective at lowering blood pressure, good compliance and lightuntoward reaction.