Upregulated Expression of hITF in Crohn’s Disease and Screening of hITF Interactant by a Yeast Two-Hybrid System

Aims To study the expression of human intestinal trefoil factor (hITF) mRNA in Crohn’s disease and to screen the cellular proteins that can interact with the hITF protein by a yeast two-hybrid system in order to explore the mechanism of hITF in protecting intestinal mucosa from injury.