Is health-related-quality of life of stroke patients influenced by neurological impairments at one year after stroke?

Aim. The aim of this study was to evaluate which neuro- logical impairments on discharge from rehabilitation ser- vices are associated with a worse outcome in terms of health related-quality of life (HRQoL) one year after stroke. Methods. We enrolled 528 first-time stroke patients in a multicenter observational study involving 18 Italian inpatients rehabilitation centers. Neurological impair- ment-related factors, socio-demographic and general clinical variables and process indicators were considered independent variables at discharge. Outcome was rep- resented by the following dependent variables of HRQoL: EuroQoL-5D questionnaire (5D-EQoL) and its derived Funding.—Partially financed by the region of Umbria (Italy) by means of funds for the regional research.