Construction of basic logic gates based on rapid detection of transferrin conformations

Abstract A simple technique for constructing different protein logic gates (OR and INHIBIT) using Fe3+ and/or Al3+ to regulate changes in the conformation of transferrin. Logic gates are easy to control and also display real-time responses to inputs. This study provides new insights into the use of different conformations to design transferrin logic gates and provides a means to further detect transferrin in serum systems.