Role of Thyroid Hormones in Stress-Induced Synthesis of Heat-Shock Proteins in the Myocardium

Thyroxine in near-physiological doses increased the content of heat-shock proteins in the myocardium and stimulated their accumulation during immobilization stress. Blockade of thyroid functions with methimazole decreased the content of heat-shock proteins in rat myocardium during stres and heat shock and prevented their accumulation during adaptation to short-term immobilizations.