Abstract 10319: The Role of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting Contrast Induced Acute Kidney Injury in Patients Presenting With Acute Coronary Syndrome

Introduction: Contrast induced acute nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI) in the setting of acute coronary syndromes (ACS) is associated with adverse outcomes including longer hospitalization, short and long-term mortality. Prevalence of CIN has been reported to be as high as 27%. Neutrophil-Lymphocyte ratio (NLR) and Platelet-Lymphocyte ratio (PLR) are inflammatory markers that have been studied in CIN. They have been validated separately in prior studies as a predictor of CIN in patients with ACS who undergo a left heart catheterization. Our study aims to further investigate the role of NLR and PLR together as markers for predicting CIN in patients with ACS. Methods: A retrospective chart review was performed on a total of 1928 patients aged 18- 90 who presented with ACS and underwent PCI between January 2011 to December 2015 at Florida Hospital Orlando. Cut-off values used for a high PLR and NLR were; PLR (>128) and NLR (>2.6). CIN was defined as increased s...