Synthesis and Evaluation of N-Phenyl-(2-aminothiazol-4-yl)acetamides with Phenoxypropanolamine Moiety as Selective β3-Adrenergic Receptor Agonists.

2012

Compounds (Ia)—(Ic) are found to be potent β3-adrenergic receptor agonists with functional selectivity over the β1- and β2-adrenergic receptors.

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