Renal release of N-acetyl-seryl-aspartyl-lysyl-proline is part of an antifibrotic peptidergic system in the kidney

Cesar A. Romero,Nitin Kumar,Pablo Nakagawa,Morel E. Worou,Tang-dong Liao,Edward L. Peterson,Oscar A. Carretero

Renal release of N-acetyl-seryl-aspartyl-lysyl-proline is part of an antifibrotic peptidergic system in the kidney

2019

Cesar A. Romero
Nitin Kumar
Pablo Nakagawa
Morel E. Worou
Tang-dong Liao
Edward L. Peterson
Oscar A. Carretero

The antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is released from thymosin-β4 (Tβ4) by the meprin-α and prolyl oligopeptidase (POP) enzymes and is hydrolyzed by angiotensin-...

Keywords:

Acetyl-seryl-aspartyl-lysyl-proline
Enzyme
Diabetes mellitus
Biochemistry
Renin–angiotensin system
Biology
Oligopeptidase
Peptide
Kidney
renal fibrosis

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