ANTIBIOTIC-RESISTANCE ANALYSIS OF PATHOGENIC BACTERIA IN INTENSIVE CARE UNITS

[Objective] To investigate the antibiotic-resistance and characteristics of respiratory pathogenic bacteria in ICUs,and to offer reasonable evidence to clinical therapy concerned.[ Methods] The clinical characteristics of isolated pathogenic strains and the results of drug sensitivity tests in patients with respiratory disease who were treated in our hospital were reviewed and analyzed.[Results] From the collected 307strains,the Gram-negative bacilli(211 strains,68.60%) were the dominant majorities.Gram-positive cocci(57 strains) and fungi(39 strains) accounted for 18.50% and 12.69%,respectively.From the results of drug sensitivity tests,most Gram-negative bacilli were becoming more and more resistant to antibitics,especially Beta-lactam antibiotics and Quinolones.Pseudomonas aeruginosa as well as acinetobacterbaumanii were becoming more and more resistant to Impenem.Additionally,Pan-resistant strains were isolated.Staphylococcus exhibited high resistance to common antibiotics,while sensitive to Vancomycin,and the resistant rate to Compound Sulfamethoxazole were below 70%.[Conclusion] These findings contribute to understanding the epidemiological characteristics and the antibiotic-resistance of the intensive care patients with secondary bacterial infection,and guiding rational use of antibiotics.