Copper(II)‐Triflate‐Catalyzed Oxidative Amidation of Terminal Alkynes: A General Approach to α‐Ketoamides

A simple and practical method for synthesizing α-ketoamides has been developed involving Cu(OTf)2-promoted oxidative amidation-diketonization of terminal alkynes with primary/secondary amines. This method has a wide substrate scope, and atmospheric oxygen acts as the oxidant.