Docetaxel albumin nanoparticle pharmaceutical composition and preparation method and application thereof

The invention discloses a docetaxel albumin nanoparticle pharmaceutical composition. The pharmaceutical composition is prepared from docetaxel, albumin and amino acid, wherein the mass ratio of albumin to docetaxel is not lager than 50, and the mass ratio of amino acid to docetaxel is not smaller than 0.5, preferably, 1. The invention further provides a preparation method of the pharmaceutical composition and application of the pharmaceutical composition in cancer treatment. The pharmaceutical composition can significantly restrain generation of 7-epi-docetaxel, and the content of 7-epi-docetaxel does not exceed 1%; in a preferred scheme, the content of 7-epi-docetaxel is only 0.72% 30 months later; the preparation method of the pharmaceutical composition is simple, and the pharmaceutical composition can be applied to treatment of various kinds of cancer and has broad market application prospects.