Characterization of an Attenuated Temperature Sensitive Feline Infectious Peritonitis Vaccine Virus

Feline infectious peritonitis (FIP) is a complex and fatal disease of cats caused by infection with feline infectious peritonitis virus (FIPV). The FIPV is a Coronavirus related to transmissible gastroenteritis virus of pigs, enteric Coronavirus of dogs, and respiratory Coronavirus of man. There is also a feline enteric Coronavirus (FECV) that replicates mainly in the intestine and causes only a mild diarrheal disease.1