APPLICATION OF INKJET-FABRICATED CRYSTALLINE C 60 PARTI- CLES GENERATING REACTIVE OXYGEN SPECIES UNDER VISIBLE LIGHT IRRADIATION TO MICROARRAY CHIPS

This paper reports microarray chips equipped with wells encapsulating three-dimensionally formed µm-size crystalline C 60 particles to generate reactive oxygen species (ROS) by irradiation of visible light, which does not affect biological materials. The crystalline C 60 particles are synthesized and immobilized on the bottoms of wells by an inkjet printing technology. The optimal inkjet conditions for synthesizing the particles to generate more ROS were found, and in the conditions the structure in which the needle-like particles were three-dimensionally formed was confirmed. The particles are capable of being used as a ROS generation source for evaluating cellular response to oxidative stress.