Leukocyte filtration lesion impairs functional coagulation in banked whole blood

BACKGROUNDWhole blood (WB) transfusion is a promising alternative to component therapy in hemostatic resuscitation. Use of banked WB requires filtration of white blood cells (leukoreduction) and an established shelf life during which WB retains coagulant capacities. The goal of this study was to def