A comparative study of remineralizing efficiency of various remineralizing agents on artificially demineralized enamel surface – An in vitro study

Aim: The aim of the present study is to evaluate different remineralizing agents on demineralized enamel surface. Materials and Methods: A total of 120 enamel samples were divided into six groups of 20 samples each. Group A - Calcium sucrose phosphate (Enafix), Group B - CPP-ACPF Containing dentrifices (GC Tooth Mousse plus), Group C - NaF with tricalcium phosphate (Clinpro Tooth Creme), Group D - Xylitol (Squigle), Group E - Positive control, Group F - Negative control. Demineralization was carried out in group A,B,C,D,F. Remineralization was carried out in group A,B,C,D. Then these samples were placed in a universal incubator at 37c between each remineralizing cycle. After seven cycles of the remineralization process surface, microhardness was measured with Vicker's micro hardness test. Statistical Analysis: The mean and standard deviation of the microhardness of tooth samples were obtained for each group and compared using one-way ANOVA. The pair-wise comparison was carried out using a post hoc Tukey test. Results: The mean microhardness values in descending order: Positive control > Xylitol > CaSP > CPP?ACPF > NaF with tricalcium phosphate > negative control. Conclusion: All remineralizing agents showed improved surface remineralization. Xylitol showed the highest potential for remineralization followed by CaSP, CPP?ACPF, and NaF with tricalcium phosphate. Keywords : Xylitol, Calcium sucrose phosphate, Casein phosphopeptide, Amorphous calcium phosphate, Sodium fluoride, Tricalcium phosphate.