Histone Deacetylase Inhibitor Treatment Increases Coronary t-PA Release in a Porcine Ischemia Model

Kristina Svennerholm,Niklas Bergh,Pia Larsson,Sverker Jern,Göran Johansson,Björn Biber,Michael Haney

Histone Deacetylase Inhibitor Treatment Increases Coronary t-PA Release in a Porcine Ischemia Model

2014

Kristina Svennerholm
Niklas Bergh
Pia Larsson
Sverker Jern
Göran Johansson
Björn Biber
Michael Haney

BACKGROUND: The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control.OBJECTIVES: The study aimed t ...

Keywords:

Acetylation
Ischemia
Histone deacetylase 5
Histone
Histone deacetylase inhibitor
Immunology
Tissue plasminogen activator
Valproic Acid
Epigenetics
Medicine
Pharmacology

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