DETERMINATION OF TRACE ELEMENTS IN HAIR OF WILSON'S DISEASE PATIENTS USING PIXE

Abstract The contents of nine elements (P, S, Ca, Fe, Cu, Zn, Pb, Se, Sr) in the hair of 52 patients with Wilson's disease (HLD) and 52 well matched healthy controls were determined by the proton induced X-ray emission (PIXE) method and they were in good agreement with published data. The apparently abnormal contents of Ca and Cu in the patient's hair were not observed. The Zn content of hair in Wilson's disease patients with splenomegaly was obviously higher than that in the matched controls ( P