Composition and levels of phospholipids in plasma from patients with exacerbation of chronic gastritis

: Blood plasma phospholipids from 45 patients with chronic gastritis and 20 healthy volunteers have been investigated. Chronic gastritis exacerbation is accompanied by essential change in the spectrum and concentration of the phospholipids. The absolute concentrations of the phospholipids and such fractions as phosphatidylcholine, phosphatidylserine, lysophosphatidylcholine, lysophosphatidylethanolamine and sphingomyelin significally increased while concentrations of phosphatidilinositol and lysophosphatidylserine decreased. The period of the remission of the disease was accompanied by a certain normalization of the level and spectrum phospholipids and literature data suggest that phospholipids and their particular fractions are involved into pathogenesis of the inflammatory process in gastric mucosa and in the process of reparative regeneration aswell.