1400 EXPRESSION OF CELL CYCLE-RELATED MOLECULAR MARKERS IN PATIENTS TREATED WITH RADICAL CYSTECTOMY FOR SQUAMOUS CELL CARCINOMA OF THE BLADDER

was created to induce an elevated blood pressure and produce a phenomenon in which renal bleeding occurs. A flexible video ureterorenoscope (URF-V: Olympus, Japan) was used in combination with the narrow band imaging (NBI) system to observe how the capillaries change within the renal pelvis and calyces before and after an increase in blood pressure and study how renal bleeding occurs and how the renal intravenous pressure is associated with it. RESULTS: An intravenous pressure of the renal vein showed a rapid increase upon occlusion. The pig’s entire kidney with occlusion of the renal vein showed development of renal bleeding immediately after occlusion. When the intravenous pressure increased above the level of 50 mmHg, bleeding was observed from local ruptures of minute vessels in the mucous layer of the renal calyx. Bleeding from the ruptured minute vessels disappeared when the renal vein occlusion was removed. CONCLUSIONS: Our experimental results suggest that congestion in the renal venous system can be a cause of hematuria. Elevated renal venous pressure-induced bleeding from locally ruptured minute vessels in the renal calyces was considered as a cause of chronic unilateral hematuria.