Total synthesis of 15-deoxoclerocidin

Abstract Enantiomerically pure 15-deoxoclerocidin ( 14 ), 15-dihydro-12- O -formylclerocidin ( 19 ) and 12- O -formyl-15,20-tetrahydroclerocidin ( 18 ) were synthesized from a methyl-substituted Wieland Miescher ketone ( 3 ).