Synthesis method of abiraterone acetate

The invention provides a synthesis method of abiraterone acetate. The synthesis method of the abiraterone acetate comprises the following steps: carrying out acetylation reaction with acetylchloride by a compound (II) to prepare a compound (III), enabling chemical exchange reaction by a compound (IV) to prepare an intermediate compound, and enabling reaction between the intermediate compound and the compound (III) to prepare a compound (I) which is abiraterone acetate. The method has the advantages of high process controllability, simple and short steps, no complicated post-treatment process, high yield, low cost and high purity of products, and is suitable for industrial production. The reaction route is as follows: the formula is as shown in the description.