A phase II trial with the combination of plinabulin (plin) pegfilgrastim (peg): Evaluation of the reversal of peg’s immune-suppressive potential by the addition of plin to peg.

Douglas W. Blayney,Stephan Ogenstad,Yuankai Shi,Ji-Feng Feng,Qingyuan Zhang,Tao Sun,Lihua Du,Lan Huang,Ramon Mohanlal

A phase II trial with the combination of plinabulin (plin) pegfilgrastim (peg): Evaluation of the reversal of peg’s immune-suppressive potential by the addition of plin to peg.

2019

Douglas W. Blayney
Stephan Ogenstad
Yuankai Shi
Ji-Feng Feng
Qingyuan Zhang
Tao Sun
Lihua Du
Lan Huang
Ramon Mohanlal

4Background: Peg is a long-acting G-CSF used for prevention of Chemotherapy Induced Neutropenia (CIN). Peg stimulates granulopoiesis in bone marrow and causes a temporary overshoot in absolute neut...

Keywords:

Pharmacology
Pathology
Perilipin
Immune system
Plinabulin
Medicine
PEG ratio
Pegfilgrastim
Neutropenia
Cancer research
Granulopoiesis
Bone marrow

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