The treatment outcome of adenocarcinoma of uterine cervix at Phramongkutklao Hospital.

Objective: To determine the survival rate of patients with adenocarcinoma of the cervix after completing treatment at Phramongkutklao Hospital. Material and Method: Retrospective review of medical records of 229 patients with adenocarcinoma of the cervix who had completed treatment at Phramongkutklao Hospital between October 1991 to September 2006. Results: Overall 2, 5 and 10-year survival for patients with adenocarcinoma of the cervix was 78.9%, 70.1% and 67.0%, respectively. The 5-year survival rates for stages I, II, III and IV were 94.6%, 76.1%, 49.2% and 0, respectively. Five-year survival of patients with locally advanced adenocarcinoma of the cervix treated with concurrent chemoradiation was comparable to that of patients treated with radiation alone (64.0 vs. 62.4%). Survival of group treated by radiation plus surgery was not significantly different to the group recieved radiation alone. There have been no serious complications from the treatments. Conclusion: Survival of patients with adenocarcinoma of the cervix shows a direct correlation with stage. The survival for each treatment modality was comparable. Adjuvant hysterectomy after radiation in adenocarcinoma of the cervix stage IIB and IIIB did not improve long term survival. Keywords: Adenocarcinoma, Cervical cancer, Survival