Osimertinib therapy as first-line treatment before acquiring T790M mutation: from AURA1 trial
2018
First- or second-generation EGFR tyrosine kinase inhibitors (EGFR-TKI) have been the first-line treatment for NSCLC harboring EGFR mutation (1-6), however almost all patients inevitably acquire resistance during EGFR-TKI therapy.
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