Clinical and neurophysiological peculiarities of tumor-related epilepsy

Detection and correction of structural tumor-associated epilepsy remain relevant at the present time. Seizures occur in 75–90% of cases in patients with gliomas of malignancy’s various degrees. The aim of this work was to clarify the links of pathogenesis and clinical and neurophysiological features of structural epilepsy in intracerebral tumors. Materials and methods. We examined 23 patients with intracerebral tumors and symptomatic epilepsy. Results. Epileptiform activity was registered in 2 or more regions in more than half of the patients — 12 people (52.18%), and 7 of them (58.3%) it spread to neighboring leads. No association was found between the size of the tumor and the number of attacks. Conclusions. Grade I–II tumors predominate among patients with tumor-related epilepsy. In this population with a high frequency after surgery, both tumor control and freedom from seizures can be achieved. It is necessary to manage this group of patients after surgery with regular neurophysiological monitoring (MRI, positron-emission tomography and video-EEG monitoring) to correct antiepileptic therapy and maintain a high level of quality of life.