Мышечная дисфункция: медико-социальные и патогенетические аспекты. Фокус на митохондрии

The steady increase in the number of cases of diseases associated with disorders of the structure and functions of the striated muscles, a significant percentage of complications and the complex character of the pathogenesis of muscle dysfunction necessitate the search for new pharmacotherapeutic targets for the correction of this condition. The significant role of mitochondria in the functioning of cells, including skeletal muscle, as well as the direct relationship of mitochondria with other elements of the pathogenetic chain of muscle dysfunction, make them a promising point of application for the action of both existing and newly developed drugs that can restore the activity of the striated muscle in conditions of muscle dysfunction.