Effect of chest pain center construction on prognosis of patients with acute ST-segment elevation myocardial infarction undergoing PPCI

Objective To study the effect of chest pain center construction on prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing direct percutaneous coronary intervention (PPCI). Methods Seventy-three patients with STEMI treated in one year before the construction of chest pain center were enrolled as the control group. Ninety-five patients with STEMI treated in eight months after the construction of chest pain center were enrolled as observation group. Both groups were treated with PPCI. The portal to balloon dilatation (D- to-B) time, incidence of heart failure during hospitalization, and 6-minute walking test distance (6-MWT) in six months after operation were compared between two groups. Results The D-to-B time in control group was (122.24±36.05) min, while it is (73.15±22.38) min in observation group, and there was a statistical difference between two groups (P<0.05). The incidences of heart failure during hospitalization in control group and observation group were 21.92%(16/73) and 8.42%(8/95) respectively, and the difference was sitatistically significant (P<0.05). 6-MWT in six months after operation was (398.15±63.11) m in control group and (486.02±56.30) m in observation group, and the difference was sitatistically significant (P<0.05). Conclusion The construction of chest pain center is suitable for the treatment of STEMI patients, which can significantly shorten the D-to-B time, reduce heart failure during hospitalization, and improve the prognosis. Key words: Acute ST-segment elevation myocardial infarction; Chest pain center construction; Direct percutaneous coronary intervention; Prognosis