Pharmaceutical preparation of recombinant factor VIII lyophilized without albumin as a stabilizer

The present invention recombinant human coagulation factor VIII freeze relates to a dry formulation, the person as a stabilizer (stabilizer) to the activity during freeze-dried to stabilize the labile proteins, recombinant human coagulation factor VIII blood derived albumin is used as the hemophilia treatment , 6 ~ 100 mM arginine (L-arginine), 3.5 ~ is made 50 mM isoleucine (L-isoleucine), using a mixture of 10 ~ 100 mM glutamic acid (L-glutamic acid) was freeze-dried instead of using. Factor VIII, recombinant blood coagulation Factor VIII, freeze-dried, albumin, amino acids, arginine, isoleucine, glutamic acid