Determination of PCQS by HPLC and its application to the analysis of Yusho patient blood and toxic rice oil and to the distribution of synthetic PCQS in mice

An excellent separation of six PCQ skeletal isomers was achieved by HPLC. This method was applied to the analysis of Yusho patient blood, toxic rice oil causing Yusho and various tissues and feces of mice dosed with synthetic PCQs.