Modification of the pendant ring of podophyllotoxin
1982
An improved route to quinonoid analogues of podophyllotoxin has been devised. Derivatives have been characterised by HPLC, NMR, and mass spectrometry; these include compounds in which the original reactivity of the lignan is modified by remote substition, which also retain the physiologically active configuration in the presence of bases.
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KQI