Revisión de Creutzfeld-Jakob a propósito de dos casos clínicos en el Hospital Universitario San Ignacio
2016
Creutzfeldt-Jakob disease is a fatal and untreatable neurodegenerative disorder that is part of the so-called spongiform encephalopathies, which is caused by the abnormal accumulation of PrP protein (called PrPSc) in the central nervous system. The most common human prion disease is sporadic form of Creutzfeldt-Jakob, whose appearance has been associated with environmental effects or unknown and random genetic events that result in the spontaneous production of PrP in the brain. In this work we will present two Clinical cases of two woman who visited the emergency room of the hospital Universitario San Ignacio, in which a rapidly progressive encephalopathy caused by Creutzfeldt-Jakob disease is suspected.
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