Malnutrition and Host Defense

This at least I clearly know: that bread has different effects in the human body according as it is fi ne or coarse, made of wheat winnowed or unwinnowed, mixed with much or little water, kneed much or not at all, baked thoroughly or underbaked—and a thousand other differences besides. If one fails to consider these points or having considered does not understand them, how can he know anything about human disease?