Esterase-Sensitive Glutathione Persulfide Donor
2018
An esterase-sensitive glutathione persulfide (GSSH) donor (BW-GP-401) is described. The release profile was studied by monitoring the formation of lactone and direct trapping of GSSH with 1-fluoro-2,4-dinitrobenzene (DNFB). The donor was examined for its inhibitory effect toward glyceraldehyde 3-phosphate dehydrogenase (GAPDH). Under highly oxidative conditions, the donor also shows cytoprotective effects in H9c2 cardiomyocytes.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
32
References
17
Citations
NaN
KQI