PReS-FINAL-2321: Clinical manifestations of granulomatosis with polyangiitis in 8 children from south-east region of Poland

Granulomatosis with polyangiitis (GPA) is a necrotising granulomatous vasculitis affecting the small and medium blood vessels in particular of airways and kidneys. The incidence of GPA in Europe is 25-150 per 1 million per year. This disease typically occurs in the 4th or 5th decades of life and in children it usually cause diagnostic and therapeutic difficulties. Subglottic stenosis and nasal deformity are frequently registered in this group of young patients.