Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin–β-catenin
2011
During development, groups of cells sometimes have to order themselves relative to a tissue in a coordinated manner, and this is true of ommatidial cells in the eye. Using a genetic and molecular approach, the Nemo kinase is shown to be involved in regulating the rate of ommatidial rotation; the study also links this event to cellular interaction through cadherin, important for coordinating reorientation.
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