Skeletal Muscle Mitochondrial Function is Determined by Burn Severity, Sex and Sepsis, and is Associated with Glucose Metabolism and Functional Capacity in Burned Children

Background Restoring normal mitochondrial function represents a new target for strategies aimed at mitigating the stress response to severe burn trauma and hastening recovery. Our objective was to investigate the determinants of skeletal muscle mitochondrial respiratory capacity and function and its association with glucose metabolism and functional capacity in burned children.