FOOD PROTEIN-INDUCED ENTEROCOLITIS SYNDROME (FPIES) - A REVIEW

Food protein-induced enterocolitis syndrome (FPIES) is an under-recognised and frequently misdiagnosed syndrome ‐ characterised by severe protracted diarrhoea and/or vomiting and frequently associated with additional symptoms such as pallor and/or lethargy ‐ which has its onset soon after the ingestion of the particular food protein. FPIES represents a severe cell-mediated, gastrointestinal food hypersensitivity. Although typically ascribed to to cow’s milk and soy, FPIES has been described after the ingestion of a wide range of food proteins.