Enantioselective Synthesis of Planar Chiral Pyridoferrocenes via Palladium-Catalyzed Imidoylative Cyclization Reactions
2018
A highly efficient synthesis of planar chiral pyrido[3,4-b] ferrocenes by a palladium-catalyzed enantioselective isocyanide insertion/desymmetric C(sp2)–H bond activation reaction was developed. Various planar chiral pyridoferrocenes were obtained in high yields with good to excellent enantioselectivity under mild conditions (up to 99% yield, 99% ee), enabled by a unique SPINOL-derived phosphoramidite ligand.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
39
References
36
Citations
NaN
KQI