Combined Medical Treatment Of Chronic Pancreatitis

Chronic pancreatitis (CP) is a chronic and permanently progressive non-infectious pancreas inflammation, which is accompanied by destruction and fibrosis of its parenchyma. Even though many etiological factors of CP, such as alcohol consumption, smoking, ductus pancreaticus obstruction, genetic factors and others, are known, pathophysiological mechanisms of the disease are always intrapancreatic activation of digestive enzymes, inflammation and exocrine insufficiency. Recurrent or persistent abdominal pain, as well as exocrine and endocrine insufficiency, are characteristic to CP.