Quantitative detection of MMP-2 and relationship of the clinical features and prognosis of lung cancer

Objective is to discuss (MMP-2) relationship of matrix metalloproteinase-2 and lung cancer invasion, metastasis and prognosis. Methods: use flow immunoassay for the quantitative detection of MMP-2 expression in 28 cases of benign lung lesions and 78 cases of lung cancer. Results: MMP 2-expression promotes lung cancer is higher than benign lesions (p <0.05), and there is a significant correlation (p <0.05) of lung cancer clinical stage and histological grade. Conclusion: The high expression of MMP-2 promotes the invasion and metastasis of lung cancer is, the higher the value is, the higher the clinical stage is, and the lower the tissue differentiation is, suggesting that MMP-2 not only can be used as indicators of lung cancer, but also is effective prognosis.