Antimicrobial therapy and local toxicity of intraventricular administration of vancomycin in a neonate with ventriculitis

Infection is the most common complication and cause of failure of cerebrospinal fluid (CSF) shunt devices used to control hydrocephalus. A male newborn was admitted for treatment of congenital occlusive hydrocephalus by means of a ventriculo-peritoneal shunt. A day later, the skin area around the si