Synthesis of ethyl 2,6-diacetamido-2,3,6-trideoxy-α-D-ribo-hexopyranoside, a derivative of the diamino-sugar component of the antibiotic nebramycin factor 6

Derivatives of a new diaminotrideoxy-D-hexose, a carbohydrate component of the pseudotrisaccharide antibiotic nebramycin factor 6 have been prepared; the synthesis is based on a conjugate 1,4-addition of azide ion on the α,β-unsaturated ketone (2).