Predictors of early diagnosis of obesity hypoventilation syndrome among patients with sleep disordered breathing

Abstract Background Determine predictors of early diagnosis and prevalence of OHS among patient with sleep disordered breathing (SDB) at Mansoura SDB unit. Aim of work Determine predictors of early diagnosis and prevalence of OHS among patient with sleep disordered breathing (SDB) diagnosed at Mansoura SDB unit. Patients and methods The study population consists of 212 patients referred to Mansoura University SDB unit for investigation of possible SDB. All patients were subjected to the following: Clinical evaluation, Pulse oximeter, Erect awake ABG, Spirometry and Polysomnography. Results It was found that; The overall prevalence of OHS in studied cases was 13.2% (28 out of 212) and the prevalence of SDB in all studied cases was 83.02% (176 out of 212), 15.91% (28 out of 176) with OHS. The following predictors can be used for early diagnosis of OHS; a cutoff point of 93% of erect awake SpO 2 with sensitivity of 97.1%, Specificity of 100%, p  3 with sensitivity of 85.7%, specificity of 95.6%, p  Conclusion The prevalence of OHS among patients with SDB diagnosed at Mansoura SDB unit was 15.91% and 16.67% among obese patients with SDB. The following cutoff points can be used as promising predictors for early diagnosis of OHS: Erect awake SpO 2 3  > 28 mmol/L and AHI > 46.4.