Polymorphism of valsartan and preparation method of polymorphism of valsartan

The invention belongs to the technical field of pharmaceutical chemistry, and discloses two new crystal forms E and F of valsartan and a preparation method of the two new crystal forms of valsartan. XRD (X-ray diffraction), Microscopes Raman spectrometer, infrared spectrum, DSC (differential scanning calorimeter), TGA (thermo gravimetric analyzer), DVS (dynamic vapor sorption instrument) and the like are adopted to perform comprehensive characterization on the new crystal forms. Good physicochemical properties and patent medicine performance of the new crystal forms are observed. The preparation method of new crystal forms of valsartan provided by the invention is simple, easy to control, and good in repeatability, and can obtain a target crystal form steadily.