A Comparative Study of Intraoperative Brain Relaxation with Thiopentone & Propofol for Supratentorial Tumour Surgery

Supratentorial tumours are space occupying lesions that can increase the mass of the brain by swelling, Brain being inside a tight skull can produce vascular compromise to the normal brain tissue inside. This swelling can also cause increased bleeding during the procedure of debulking of the tumour. Manoeuvres to reduce brain swelling by hyperventilation, use of osmotic diuretics and Thiopentone have been tried. Thiopentone is known for its brain protective action and also brain relaxation that can facilitate surgery, reduce bleeding . This study was designed to compare the effects of Thiopentone and Propofol on brain relaxation.